When there’s not an obvious best treatment for a chronic condition, humans often use trial and error, moving through a list of treatments until one hits. Research into human decision-making suggests that this unstructured approach introduces numerous biases.
Industrial medicine views random control trials (RCTs) as the gold standard for determining the efficacy of medications. The thinking goes: blinding, controls/placebos and regular reporting produce objectively reliable, generalizable results. Yet critics argue that RCTs, at least the ones that clinicians habitually read in the reprints of medical journal articles shared by drug company reps, […]