Medicine’s history is often portrayed as a sequence of discoveries, all made in laboratories. In fact, though, the biggest changes in US medicine over the last 200 years were propelled by forces beyond medicine, specifically, in media. How medicine’s stakeholders communicated in different eras — in formats including medicine shows, newspapers, cars, telephones, medical journals, and TVs — determined what, and how much, was communicated. Where information flows, medicine follows: now social media, biomonitors and AI are ushering in a new age, one of patient generated medicine.