Tolstoy on unique illnesses and self-serving caregivers

Amid the tumbling flood of gossip, duels, dinner parties, battles, clothing choices, serf-floggings and broken engagements that comprises most of Leo Tolstoy’s War and Peace sit quiet islands of wisdom about how humans’ needs knit together to form social instruments and institutions. Resting on the bedrock of human nature, these islands are as ageless as […]

Why aren’t n-of-1 experiments already common for chronic conditions?

Because many treatments’ effects vary depending on the individual, some researchers argue that effectiveness should be evaluated per patient. Yet a simple evaluation protocol that’s been tested and refined for 30 years, called an n-of-1 trial, is rarely used. Why?

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