Research into best practices for personal experiments (aka n-of-trials)

“We spend so much effort on precision in diagnosis, yet we have very little precision about treatment,” observed Dr. Eric Larson, a professor of medicine at the University of Washington.  Experts say that even for widely-studied drugs, “the trial and error approach to medicine is not cost efficient because several of the most prominent drugs […]

Looking for an N-of-1 service for a single patient trial?

Recognizing that most top selling drugs in the US benefit only a fraction of treated patients, some researchers have advocated single patient drug trials for nearly 30 years. An n-of-1 trial applies standard scientific methodology — including placebos, blinding, random block rotation, crossovers, washouts and statistical analysis — to determine a drug’s efficacy for an […]

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